Figure 1: Schematic workflow of the differential FTIR imaging tissue characterization for thoracal tumours. | Scientific Reports

Figure 1: Schematic workflow of the differential FTIR imaging tissue characterization for thoracal tumours.

From: Spatial and molecular resolution of diffuse malignant mesothelioma heterogeneity by integrating label-free FTIR imaging, laser capture microdissection and proteomics

Figure 1

Tissue annotation by FTIR imaging for lung tumours and thoracal tumours is illustrated. The classifiers for lung tumours and thoracal tumours (shaded in grey) were previously published and reprinted from Großerueschkamp et al. Analyst 201536. In a first classifier, the pathologic regions were identified. In a second classifier, the different tumour classes of the pathologic region are differentiated. Finally in the third classifier, a differential diagnosis of the tumour subtypes is provided. The DMM subtype classifier was trained especially for this study based on newly acquired samples. This is an important step establishing a differential and predictive thoracal tissue classifier.

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