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An illustration of a tumor surrounded by T cells bearing cytokine 'backpacks'. The cytokine-delivery system developed by Tang et al. releases cytokines specifically at the tumor after T cells recognize a tumor antigen (p 707). Image credit: Yutao Dong
Despite spooking investors, new insights into DNA repair and the CRISPR gene-editing system are part and parcel of its progress from research tool to human therapy.
Life sciences company decision-makers can effectively manage disputes using appropriate dispute resolution techniques without resorting to expensive, complex, and uncertain litigation.
Cas9-induced double stranded breaks can cause large deletions near the target site and more complex genomic rearrangements in mouse and human stem cells.
