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Showing 1–23 of 23 results

  • Gene loss is followed by the rapid emergence of new phenotypes owing to compensatory evolution, finds a recent study using experimental evolution of budding yeast lineages.

    • Linda Koch
    Research Highlights
    Nature Reviews Genetics
    Volume: 23, P: 393

    • Grant Miura
    Research Highlights
    Nature Chemical Biology
    Volume: 14, P: 413

    • Grant Miura
    Research Highlights
    Nature Chemical Biology
    Volume: 18, P: 1291

  • A study reports on the suitability of the yeast Saccharomyces cerevisiae as a platform for the assembly and maintenance of diverse RNA virus genomes, including SARS-CoV-2.

    • Linda Koch
    Research Highlights
    Nature Reviews Genetics
    Volume: 21, P: 388

  • A recent study re-casts proteomic analyses as a DNA sequencing problem; by fusing in vivo-expressed proteins to their encoding mRNA, molecular interactions can be identified and quantified through high-throughput nucleic-acid sequencing.

    • Linda Koch
    Research Highlights
    Nature Reviews Genetics
    Volume: 22, P: 2

    • Grant Miura
    Research Highlights
    Nature Chemical Biology
    Volume: 12, P: 763

    • Terry L. Sheppard
    Research Highlights
    Nature Chemical Biology
    Volume: 10, P: 408

  • A recent report inSciencedescribes the design and construction of an entire, engineered eukaryotic chromosome in yeast.

    • Eytan Zlotorynski
    Research Highlights
    Nature Reviews Molecular Cell Biology
    Volume: 15, P: 298

    • Grant Miura
    Research Highlights
    Nature Chemical Biology
    Volume: 10, P: 794

  • A simple microfluidic device allows long-term imaging of single budding yeast cells.

    • Tal Nawy
    Research Highlights
    Nature Methods
    Volume: 9, P: 438

  • The elimination of all cross-talk in a signaling pathway turns a yeast cell into a model cell that can sense and report on metabolites.

    • Nicole Rusk
    Research Highlights
    Nature Methods
    Volume: 16, P: 457

  • The commonly used budding yeast strain W303 carries a mutant RAD5 gene (rad5-535), but numerous laboratories use a strain corrected for the mutation. This has resulted in different phenotypes of W303 cells in similar experiments. Here, we aim to raise awareness of the issue to ensure data reproducibility and interpretation.

    • Menattallah Elserafy
    • Sherif F. El-Khamisy
    Comments & Opinion
    Nature Reviews Molecular Cell Biology
    Volume: 19, P: 343-344

  • Mitochondria are critical for cellular energy generation and house oxidative phosphorylation (OXPHOS) complexes, which are under dual genetic control. A study finds that transcript translation and complex assembly are partitioned, and OXPHOS complexes III, IV and V are built at spatially defined regions of the mitochondrial inner membrane.

    • Luke E. Formosa
    • Michael T. Ryan
    News & Views
    Nature Cell Biology
    Volume: 20, P: 511-513