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Showing 1–23 of 23 results

    • Yiyun Song
    Research Highlights
    Nature Chemical Biology
    Volume: 16, P: 225

  • A new paper in Science reports that human genomes encode a large repertoire of retroviral envelope-derived proteins, with potential roles in protecting from infection by other retroviruses.

    • Darren J. Burgess
    Research Highlights
    Nature Reviews Genetics
    Volume: 24, P: 2

  • This study suggests that primary SARS-CoV-2 exposure may protect against reinfection in rhesus macaques.

    • Ashley York
    Research Highlights
    Nature Reviews Microbiology
    Volume: 18, P: 477

  • A recent study found that viral cap snatching generates host–virus chimeric proteins during infection.

    • Ashley York
    Research Highlights
    Nature Reviews Microbiology
    Volume: 18, P: 477

    • Zoltan Fehervari
    Research Highlights
    Nature Immunology
    Volume: 22, P: 103

  • This study reports a structure of the respiratory syncytial virus (RSV) polymerase complex, providing atomic-level insights into transcription and replication of the RSV genome.

    • Ashley York
    Research Highlights
    Nature Reviews Microbiology
    Volume: 17, P: 646

  • In this study, Patel, Whiteet al. discover that the hepatitis B virus pre-genome RNA contains specific nucleotide motifs that mediate interactions with the viral capsid protein to drive nucleocapsid assembly.

    • Ashley York
    Research Highlights
    Nature Reviews Microbiology
    Volume: 15, P: 451

    • Ashley York
    Research Highlights
    Nature Reviews Microbiology
    Volume: 15, P: 133

    • Michelle Montoya
    Research Highlights
    Nature Structural & Molecular Biology
    Volume: 19, P: 867

  • Influenza buds by an ESCRT-independent mechanism that involves the matrix protein M2.

    • Rachel David
    Research Highlights
    Nature Reviews Microbiology
    Volume: 8, P: 757

  • Looking at the effects of proteins encoded by DNA tumour viruses on the host genome could aid the interpretation of high-throughput sequencing data from cancer samples.

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 12, P: 582

  • This month’s Under the Lens discusses a few of the growing number of recent molecular simulation studies that have made substantial contributions towards our mechanistic understanding of the spike protein of SARS-CoV-2.

    • Conrado Pedebos
    • Syma Khalid
    Comments & Opinion
    Nature Reviews Microbiology
    Volume: 20, P: 192

  • This month’s Under the Lens discusses how structural studies of the SARS-CoV-2 spike glycoprotein might guide a path towards a vaccine.

    • Nawsad Alam
    • Matthew K. Higgins
    Comments & Opinion
    Nature Reviews Microbiology
    Volume: 18, P: 414

  • The Lassa virus nucleoprotein coats the viral genome to make a template for RNA synthesis. A study shows that it also binds the 'cap' structure of cellular messenger RNAs and directs immune evasion using a novel mechanism. See Article p.779

    • Félix A. Rey
    News & Views
    Nature
    Volume: 468, P: 773-775

  • How the novel influenza H7N9 virus crossed species barrier from avian to human is intriguing. Extrapolation from previous studies on H5N1 can be misleading as illustrated by crystallographic studies on the H7 hemagglutinin with G226L substitution; crystal structure of the neuraminidase N9 showed that R294K substitution interferes with binding to sialic acid or antiviral drugs and reduces viral fitness.

    • Kwok-Yung Yuen
    Research Highlights
    Cell Research
    Volume: 23, P: 1335-1336

  • A novel coronavirus, the Middle East respiratory syndrome coronavirus, recently emerged through zoonotic transmission, causing a severe lower respiratory tract infection in humans. In two recent papers, one published in Cell Research, the crystal structure of the viral receptor-binding domain in complex with the host CD26/dipeptidyl peptidase 4 receptor has now been characterized.

    • Berend Jan Bosch
    • V Stalin Raj
    • Bart L Haagmans
    Research Highlights
    Cell Research
    Volume: 23, P: 1069-1070