Patients with acute kidney injury (AKI) complicating multiple myeloma often have poor outcomes. In this Review, Hutchison et al. discuss the pathogenic role of monoclonal free light chains in inducing proximal tubular damage and cast nephropathy in patients with multiple myeloma. The authors also provide an update on the diagnostic approaches to patients with AKI complicating multiple myeloma.
- Colin A. Hutchison
- Vecihi Batuman
- Paul W. Sanders
