The clear-cell variant is the most common subtype of renal cell carcinoma (RCC) and, as discussed in this Review, accurate diagnosis of clear cell RCC is important and can be a challenge. Valera and Merino describe the clinical, pathological, and radiological features of clear cell RCC as well as the factors important to prevent misdiagnosis of this disease.
- Vladimir A. Valera
- Maria J. Merino