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Showing 1–4 of 4 results
Advanced filters: Author: "A. G. Uitterlinden" Clear advanced filters
  • André Uitterlinden and colleagues report a genome-wide association study for age at natural menopause, from the Rotterdam Study and TwinsUK, with replication in additional cohorts. They report three loci associated with age at natural menopause, which is a known risk factor for several cancers, osteoporosis and cardiovascular disease.

    • Lisette Stolk
    • Guangju Zhai
    • André G Uitterlinden
    Research
    Nature Genetics
    Volume: 41, P: 645-647
  • Fernando Rivadeneira and colleagues report findings from a large-scale meta-analysis of genome-wide association studies for bone mineral density. The loci identified in this study map to genes in signaling pathways relevant to bone metabolism and highlight the complex genetic architecture underlying osteoporosis.

    • Fernando Rivadeneira
    • Unnur Styrkársdottir
    • André G Uitterlinden
    Research
    Nature Genetics
    Volume: 41, P: 1199-1206
  • A new, very large genome-wide association study has uncovered many novel genetic factors associated with circulating lipid levels. The success of this study came partly from analysing many samples, but mostly from including individuals of non-European ancestry. So, why is studying genetic diversity important and how can it help to fight cardiovascular disease?

    • André G. Uitterlinden
    News & Views
    Nature Reviews Cardiology
    Volume: 19, P: 289-290