A growing body of evidence indicates that monocytes, specifically intermediate (CD14++CD16+) monocytes, contribute to the development of atherogenesis and increase in number with worsening renal function. In this Review, Heine and colleagues on behalf of the EURECA-m working group of the ERA–EDTA, describe the developmental and functional characterization of monocyte subsets, with particular focus on prominent subsets in atherosclerosis and chronic kidney disease.
- Gunnar H. Heine
- Alberto Ortiz
- Danilo Fliser
