Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–6 of 6 results
Advanced filters: Author: "Alfonso Valencia" Clear advanced filters

  • Here, the authors evaluate the performance of AlphaFold2 and its predicted structures on common structural biological applications, including missense variants, function and ligand binding site prediction, modeling of interactions and modeling of experimental structural data.

    • Mehmet Akdel
    • Douglas E. V. Pires
    • Pedro Beltrao
    ResearchOpen Access
    Nature Structural & Molecular Biology
    Volume: 29, P: 1056-1067

  • Disease comorbidity is attracting increasing attention, but the involvement of molecular factors in forecasting risk of a disease in the presence of other diseases is poorly understood. Here the authors build a disease interaction network based on gene expression profile and discover new comorbidity relationships in patient subgroups.

    • Jon Sánchez-Valle
    • Héctor Tejero
    • Alfonso Valencia
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13

  • Functional interactions between proteins and within proteins results in co-evolutionary signatures in amino acid sequences that serve as clues to various forms of interdependence. This Review discusses the principles and distinctions of the large range of computational tools to analyse protein co-evolution and the biological insight that they are providing.

    • David de Juan
    • Florencio Pazos
    • Alfonso Valencia
    Reviews
    Nature Reviews Genetics
    Volume: 14, P: 249-261

    • Janet M Thornton
    • Alfonso Valencia
    • Torsten Schwede
    Comments & Opinion
    Nature Structural & Molecular Biology
    Volume: 24, P: 431-432