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Advanced filters: Author: "Andrea Viale" Clear advanced filters

  • After expression of the PML–RAR oncogene in haematopoietic stem cells, p21 is necessary to limit cell cycle progression and thus limit the accumulation of DNA damage which would otherwise limit the self-renewal of leukaemic stem cells and prevent the development of leukaemia

    • Andrea Viale
    • Francesca De Franco
    • Pier Giuseppe Pelicci
    Research
    Nature
    Volume: 457, P: 51-56