Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–3 of 3 results
Advanced filters: Author: "Ann Marie Schmidt" Clear advanced filters

  • Injury to the vasculature is an important adverse outcome in diabetes. In this Review, Yan et al. explore how advanced glycation end-products and their main receptor, RAGE, might have roles in the development of diabetes and some of its complications–nephropathy, atherosclerosis and inflammatory response–through activation of inflammatory signaling cascades.

    • Shi Fang Yan
    • Ravichandran Ramasamy
    • Ann Marie Schmidt
    Reviews
    Nature Clinical Practice Endocrinology & Metabolism
    Volume: 4, P: 285-293

  • The receptor for advanced glycation endproducts (RAGE) was first identified as a signal transduction receptor for the advanced glycation endproducts (AGEs) of proteins and lipids. Experiments using transgenic mouse models, pharmacological blockade of RAGE and genetic modification or deletion of RAGE indicate a key role for RAGE in the pathogenesis of various nephropathies including diabetic nephropathy. In this Review, D'Agati and Schmidt discuss the evidence linking RAGE to diabetic nephropathy and chronic kidney disease.

    • Vivette D'Agati
    • Ann Marie Schmidt
    Reviews
    Nature Reviews Nephrology
    Volume: 6, P: 352-360

  • Long-term diabetes increases the likelihood of developing complications such as macrovascular disease, nephropathy, retinopathy and neuropathy. This Review highlights the range of pathologies that are precipitated by hyperglycaemia and discusses recent developments in preclinical and clinical research for each of these complications.

    • Nigel A. Calcutt
    • Mark E. Cooper
    • Ann Marie Schmidt
    Reviews
    Nature Reviews Drug Discovery
    Volume: 8, P: 417-430