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Showing 1–4 of 4 results
Advanced filters: Author: "Anne C. Ferguson-Smith" Clear advanced filters

  • How much transgenerational epigenetic inheritance takes place, and what impact does this have on organisms? We asked five leading researchers — working on key model organisms and on human disease — for their views.

    • Ueli Grossniklaus
    • William G. Kelly
    • Susan Lindquist
    Reviews
    Nature Reviews Genetics
    Volume: 14, P: 228-235

  • Genomic imprinting has provided insights into epigenetic principles that apply in many contexts. This Timeline highlights lessons for developmental gene regulation by looking back at the emergence of our understanding of imprinting, particularly in mammals, and commenting on current questions and recent progress.

    • Anne C. Ferguson-Smith
    Reviews
    Nature Reviews Genetics
    Volume: 12, P: 565-575

  • Adding methyl groups to DNA is a way of regulating some genes and genomic sequences. Structural analysis reveals that the enzyme complex that mediates this process shows unexpected sequence specificity.

    • Anne C. Ferguson-Smith
    • John M. Greally
    News & Views
    Nature
    Volume: 449, P: 148-149

  • This commentary provides a nuanced discussion on the conceptual framework to study epigenetic mechanisms that regulate brain function and plasticity. By drawing from examples in genomic imprinting, the authors highlight the challenges facing epigenetics research in the context of neuroscience.

    • Michael J Meaney
    • Anne C Ferguson-Smith
    Comments & Opinion
    Nature Neuroscience
    Volume: 13, P: 1313-1318