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Showing 1–4 of 4 results
Advanced filters: Author: "Asifa Akhtar" Clear advanced filters
  • Researchers from across the field consider the new concepts that have emerged during the past decade of molecular cell biology research, and the key challenges still to be met.

    • Asifa Akhtar
    • Elaine Fuchs
    • Marino Zerial
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 12, P: 669-674
  • Many organisms have evolved dosage compensation mechanisms to normalize gene expression levels when copy numbers of sex chromosomes and autosomes are unequal. This Review discusses how multiple epigenetic processes fine-tune the twofold upregulation of gene expression across the entire male X chromosome ofDrosophila melanogaster.

    • Thomas Conrad
    • Asifa Akhtar
    Reviews
    Nature Reviews Genetics
    Volume: 13, P: 123-134
  • The positioning of individual genes within the nucleus affects their expression levels. The inner face of the nuclear envelope is key to this method of regulating expression, with active genes preferentially locating to nuclear pores in a manner that might be heritable.

    • Asifa Akhtar
    • Susan M. Gasser
    Reviews
    Nature Reviews Genetics
    Volume: 8, P: 507-517