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Showing 1–6 of 6 results
Advanced filters: Author: "B. Martin" Clear advanced filters
  • Cellobiose dehydrogenases (CDHs) cooperate with lytic polysaccharide monooxygenases (LPMOs) to catalyse cellulose degradation. Here Tan et al. define the electron transfer pathway in CDH, providing a structural analysis of CDH conformers and of the interaction between CDH and LPMO during cellulose depolymerisation.

    • Tien-Chye Tan
    • Daniel Kracher
    • Christina Divne
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-11
  • The mammalian mitochondrial transcription factor A (TFAM) is encoded in the nucleus and imported into mitochondria, where it functions as an activator of mtDNA transcription and packages mtDNA into DNA-protein aggregates called mitochondrial nucleoids. Two studies in this issue reveal that TFAM shapes mtDNA into a sharp U-turn, providing a molecular mechanism for its dual roles in the expression and maintenance of mtDNA.

    • B Martin Hallberg
    • Nils-Göran Larsson
    News & Views
    Nature Structural & Molecular Biology
    Volume: 18, P: 1179-1181
  • With improved breeding and cultivation, ruminant animals can yield food that is better for people and the planet, say Mark C. Eisler, Michael R. F. Lee and colleagues.

    • Mark C. Eisler
    • Michael R. F. Lee
    • Michael Winter
    Comments & Opinion
    Nature
    Volume: 507, P: 32-34
  • The cognitive abnormalities observed in Alzheimer disease (AD) may be linked to alterations in oscillatory rhythmic activity and neuronal network hypersynchrony. Palop and Mucke review these links and explore how countering these network abnormalities and interneuron dysfunction may hold therapeutic potential for AD.

    • Jorge J. Palop
    • Lennart Mucke
    Reviews
    Nature Reviews Neuroscience
    Volume: 17, P: 777-792