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Showing 1–3 of 3 results
Advanced filters: Author: "Barbara Wold" Clear advanced filters

  • Next-generation sequencing technologies are beginning to facilitate genome sequencing. But in addition, new applications and new assay concepts have emerged that are vastly increasing our ability to understand genome function.

    • Barbara Wold
    • Richard M Myers
    Comments & Opinion
    Nature Methods
    Volume: 5, P: 19-21

  • The nematode wormCaenorhabditis eleganshas long been a key model organism, not least owing to its powerful genetic toolkit. Recent technological advances — for example, in manipulating gene expression and physiology — further increase the power of the worm as a model.

    • Xiao Xu
    • Stuart K. Kim
    Reviews
    Nature Reviews Genetics
    Volume: 12, P: 793-801

  • Transient receptor potential (TRP) channels are the most prominent family of nociceptive ion-channel transducer proteins. This Review highlights evidence supporting particular TRP channels as targets for analgesics, indicates the likely efficacy profiles of TRP-channel-acting compounds and looks at recent clinical trials with TRP-channel-acting drugs.

    • Ardem Patapoutian
    • Simon Tate
    • Clifford J. Woolf
    Reviews
    Nature Reviews Drug Discovery
    Volume: 8, P: 55-68