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Showing 1–4 of 4 results
Advanced filters: Author: "Boris Lenhard" Clear advanced filters

  • The improving functional annotation of genomes through the analysis of genome-wide data sets is revealing important characteristics of promoters. Similar classes of promoters are now emerging across diverse metazoan species, and novel features that contribute to gene regulation are being identified.

    • Boris Lenhard
    • Albin Sandelin
    • Piero Carninci
    Reviews
    Nature Reviews Genetics
    Volume: 13, P: 233-245

  • Three high-throughput methods allow regulatory sequences to be analyzed at single-nucleotide resolution in living cells.

    • Vanja Haberle
    • Boris Lenhard
    News & Views
    Nature Biotechnology
    Volume: 30, P: 504-506

  • Promoter strength is measured genome-wide with two high-throughput reporter assays.

    • Nevena Cvetesic
    • Boris Lenhard
    News & Views
    Nature Biotechnology
    Volume: 35, P: 123-124

  • Genome-wide discovery and characterization of core promoters has revealed that most mammalian genes are transcribed from multiple promoters, each of them starting from multiple nucleotide positions, not directed by a TATA box. The authors propose a new classification of promoters.

    • Albin Sandelin
    • Piero Carninci
    • David A. Hume
    Reviews
    Nature Reviews Genetics
    Volume: 8, P: 424-436