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Showing 1–3 of 3 results
Advanced filters: Author: "Brian J Nickoloff" Clear advanced filters

  • Granulysin, a powerful cytolytic protein secreted from immune cells, underlies an extreme and deadly response to common medications, in which the skin blisters and sloughs off. The findings may also have implications for bone marrow transplant recipients suffering from graft-versus-host disease (pages 1343–1350).

    • Brian J Nickoloff
    News & Views
    Nature Medicine
    Volume: 14, P: 1311-1313

  • Psoriasis results from cross-talk between immune cells and keratinocytes in the skin. The nature of these signals now comes to light, revealing potential roles for IL-23 and a TH17 response.

    • Brian J Nickoloff
    News & Views
    Nature Medicine
    Volume: 13, P: 242-244

  • The skin and the immune cells that it contains provide essential protection from injury and infection. This Review describes recent studies that expand our understanding of the functional role of these sentinel cells in sensing danger and mediating homeostasis and disease in the skin.

    • Frank O. Nestle
    • Paola Di Meglio
    • Brian J. Nickoloff
    Reviews
    Nature Reviews Immunology
    Volume: 9, P: 679-691