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Showing 1–4 of 4 results
Advanced filters: Author: "Brigitte Wildemann" Clear advanced filters

  • Since the launch ofNature Clinical Practice Neurologyin 2005, we have seen remarkable progress in many areas of neurology research, but what does the future hold? For this special Viewpoint article, we invited a panel of Advisory Board members and other journal contributors to outline their research priorities and predictions for the next 10 years.

    • Ralf Baron
    • Donna M. Ferriero
    • Michael Weller
    Reviews
    Nature Reviews Neurology
    Volume: 11, P: 658-664

  • Neuromyelitis optica is a CNS inflammatory disorder that predominantly affects the optic nerves and spinal cord. Jarius and Wildemann review the latest experimental and clinical evidence that supports a direct role for antibodies to aquaporin-4—the most abundant water channel in the brain—in the immunopathogenesis of this condition. The authors also evaluate the range of diagnostic tests that are currently available for the detection of these antibodies.

    • Sven Jarius
    • Brigitte Wildemann
    Reviews
    Nature Reviews Neurology
    Volume: 6, P: 383-392

  • Neuromyelitis optica (NMO) is a rare neuroinflammatory disorder that predominantly affects the optic nerves and spinal cord. NMO was originally considered to be a subtype of multiple sclerosis, but the recent discovery of NMO-specific serum autoantibodies has caused it to be reclassified as a distinct disease. In this article, Jariuset al. review clinical, serological and pathological findings in NMO, and discuss the evidence supporting an antibody-mediated mechanism in its pathogenesis.

    • Sven Jarius
    • Friedemann Paul
    • Brigitte Wildemann
    Reviews
    Nature Clinical Practice Neurology
    Volume: 4, P: 202-214

  • Susac syndrome is an important differential diagnosis in many neurological disorders, but our understanding of this rare disease has largely been limited to reports of single cases and small case series. In this article, Dörr and colleagues review all reported cases of Susac syndrome to provide a comprehensive overview of demographic, clinical and diagnostic data on this disorder. On the basis of their findings, Dörr et al. make recommendations for diagnosis and management of individuals with suspected Susac syndrome.

    • Jan Dörr
    • Sarah Krautwald
    • Ilka Kleffner
    Reviews
    Nature Reviews Neurology
    Volume: 9, P: 307-316