White adipose tissue-derived adipokines are closely associated with obesity-related exogenous factors, such as nutrition and lifestyle, and the molecular events that lead to metabolic syndrome, inflammatory and/or autoimmune conditions, and rheumatic diseases. In this Review, Dr Gualillo and colleagues discuss the progress in adipokine research, focussing on the roles of leptin, adiponectin, resistin, visfatin, and other recently identified adipokines.
- Francisca Lago
- Carlos Dieguez
- Oreste Gualillo
