In this Review, Brown et al. describe the role of biomechanical forces, including wall shear stress and plaque structural stress, in the development and progression of coronary atherosclerosis. The calculation and integration of biomechanical parameters might improve our ability to detect arterial regions at risk of atherosclerosis, enabling better identification of patients at high risk of adverse clinical events.
- Adam J. Brown
- Zhongzhao Teng
- Martin R. Bennett
