Strategies to repair damaged intervertebral discs rely on the premise that these structures can be regenerated using cellular-based approaches. Here, Huang and colleagues highlight the importance of nutrient balance for maintenance of disc cell function and question whether disc repair can be successfully achieved in degenerate human discs where nutrient supply is compromised.
- Yong-Can Huang
- Jill P. G. Urban
- Keith D. K. Luk
