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Showing 1–3 of 3 results
Advanced filters: Author: "Caroline Relton" Clear advanced filters
  • Birthweight has been found to associate with later-life health outcomes. Here the authors perform a meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in the Pregnancy And Childhood Epigenetics Consortium, identifying differentially methylated CpGs in neonatal blood that associate with birthweight.

    • Leanne K. Küpers
    • Claire Monnereau
    • Janine F. Felix
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11
  • Experimental and animal data suggest that maternal obesity adversely affects offspring health, but effects in humans are less clear. This Review evaluates the evidence for a causal effect of maternal increased adiposity and gestational weight gain on perinatal and long-term offspring outcomes in humans and explores the possible contribution of epigenetic modifications.

    • Debbie A. Lawlor
    • Caroline Relton
    • Scott M. Nelson
    Reviews
    Nature Reviews Endocrinology
    Volume: 8, P: 679-688
  • DNA methylation-based predictors of health aim to predict outcomes such as exposure, phenotype or disease on the basis of genome-wide levels of DNA methylation. The authors review applications of existing DNA methylation-based predictors and highlight key statistical best practices to ensure their reliable performance.

    • Paul D. Yousefi
    • Matthew Suderman
    • Caroline L. Relton
    Reviews
    Nature Reviews Genetics
    Volume: 23, P: 369-383