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Showing 1–5 of 5 results
Advanced filters: Author: "Chaitan Khosla" Clear advanced filters

  • At present, the only available treatment for celiac disease is a strict gluten-exclusion diet. Increasing numbers of patients are being diagnosed with celiac disease, making the need for alternative treatments even more urgent. Recent advances have improved our understanding of the molecular basis of celiac disease and new targets for rational therapy have been identified. This Review discusses concepts for new treatments and their current status.

    • Ludvig M Sollid
    • Chaitan Khosla
    Reviews
    Nature Clinical Practice Gastroenterology & Hepatology
    Volume: 2, P: 140-147

  • Certain enzymes that synthesize antibiotics play a game of pass the parcel, handing biosynthetic intermediates from one active site to another. A study reveals the dynamic nature of interactions between the enzyme domains.

    • Shiven Kapur
    • Chaitan Khosla
    News & Views
    Nature
    Volume: 454, P: 832-833

  • Enzymology has been a vital link between chemistry and biology in the second half of the twentieth century. A range of emerging scientific challenges is presenting the field with exciting opportunities to continue thriving in the future.

    • Chaitan Khosla
    Comments & Opinion
    Nature Chemical Biology
    Volume: 11, P: 438-441

  • Celiac disease has previously been regarded as a benign intestinal disorder that can be easily treated by a gluten-free diet. This Review article discusses advances in the understanding of the genetics and immunology of celiac disease, and considers evidence for the independent existence of the adaptive and innate immune response to gluten.

    • Bana Jabri
    • Ludvig M Sollid
    Reviews
    Nature Clinical Practice Gastroenterology & Hepatology
    Volume: 3, P: 516-525