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Showing 1–2 of 2 results
Advanced filters: Author: "Charles D Pusey" Clear advanced filters

  • Antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis is a common cause of acute kidney injury in the elderly. This patient group is particularly susceptible to disease-related morbidity and mortality, and to adverse effects of induction immunosuppression. A new study adds to the debate on the most appropriate way to treat this vulnerable group of patients.

    • Ruth M. Tarzi
    • Charles D. Pusey
    News & Views
    Nature Reviews Nephrology
    Volume: 7, P: 253-255

  • With the continued focus on evidence-based medicine, new randomized controlled trials (RCTs) are needed in vasculitis to improve management of these conditions. In this Opinion article, using antineutrophil cytoplasmic antibody-associated and large-vessel vasculitis as examples, Tarzi and colleagues discuss RCTs performed to date and outline important issues in trial design and future directions for the field.

    • Ruth M. Tarzi
    • Justin C. Mason
    • Charles D. Pusey
    Reviews
    Nature Reviews Rheumatology
    Volume: 10, P: 502-510