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Showing 1–2 of 2 results
Advanced filters: Author: "Cheuk-Man Yu" Clear advanced filters

  • Percutaneous transcatheter mechanical occlusion of the left atrial appendage (LAA) is a nonpharmacological treatment option for stroke prevention in patients with atrial fibrillation who cannot receive anticoagulant drugs. In this Review, Cheuk-Man Yu and colleagues present the rationale for LAA occlusion in patients with AF, the available occlusion devices and the clinical evidence for their use, and discuss the role of imaging techniques in device implantation and the management of procedural complications.

    • Cheuk-Man Yu
    • Ahmed A. Khattab
    • Bernhard Meier
    Reviews
    Nature Reviews Cardiology
    Volume: 10, P: 707-722

  • In this opinion article, the authors discuss multicentre clinical trials in Asia. Asians have been under-represented in many clinical trials; differences in cardiovascular disease risk and drug responses between Asians and white people underscore the importance of ethnicity-specific intervention testing. Challenges specific to Asia need to be addressed before Asia can rival Europe and the USA as a location-of-choice for clinical trials.

    • Joey S. W. Kwong
    • Cheuk-Man Yu
    Reviews
    Nature Reviews Cardiology
    Volume: 10, P: 355-362