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Showing 1–4 of 4 results
Advanced filters: Author: "Chia-Lin Wei" Clear advanced filters

  • Methods connecting genes to their cis-regulatory elements usually requires millions of input cells. Here the authors combine proximity ligation in ChIA-PET and transposase accessibility in ATAC-seq, reporting ChIATAC, to map interactions between open chromatin loci in low numbers of input cells.

    • Haoxi Chai
    • Harianto Tjong
    • Yijun Ruan
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • Wong and Ngan et al. characterize the expression and structural variation of SARS-CoV-2 subgenomic RNAs (sgRNAs) in diagnostic specimens from symptomatic and asymptomatic COVID-19 patients. In a series of genomic and transcriptomic analyses, the authors observe reduced sgRNA expression and a distinct set of structural deletions in asymptomatic infections compared with symptomatic infections.

    • Chee Hong Wong
    • Chew Yee Ngan
    • Chia-Lin Wei
    ResearchOpen Access
    Communications Medicine
    Volume: 1, P: 1-12