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Advanced filters: Author: "Christian Babbs" Clear advanced filters

  • Globin loci harbor genes that are expressed embryonically and silenced postnatally. Here the authors show that zeta-globin silencing depends upon selective hypoacetylation of its TAD subdomain, which blocks its interaction with the alpha-globin super-enhancer, and zeta-globin can be reactivated by acetylation.

    • Andrew J. King
    • Duantida Songdej
    • Christian Babbs
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15