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Showing 1–5 of 5 results
Advanced filters: Author: "Christophe Mulle" Clear advanced filters

  • Kainate receptors are selectively found at CA3-mossy fibre synapses, although the mechanisms regulating this compartmentalisation have yet to be determined. Here, the authors find KAR segregation is dependent on the amount of GluK2a protein and an interaction between the GluK2 C-terminal domain and N-cadherin.

    • Sabine Fièvre
    • Mario Carta
    • Christophe Mulle
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-12

  • Hippocampal synaptic dysfunctions are an early symptom of Alzheimer’s disease. Here, the authors find adenosine A2A receptors are up-regulated in APP/PS1 model mice and that deleting or blocking receptor activity helps alleviate plasticity and memory impairments.

    • Silvia Viana da Silva
    • Matthias Georg Haberl
    • Christophe Mulle
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-11

  • The circuitry of the hippocampal CA3 region has long been hypothesized to be well suited to the storage of memories. Mulle and colleagues provide an update on the known types and mechanisms of synaptic plasticity in CA3 and describe evidence for their roles in memory formation and retrieval.

    • Nelson Rebola
    • Mario Carta
    • Christophe Mulle
    Reviews
    Nature Reviews Neuroscience
    Volume: 18, P: 208-220

  • Our understanding of the functional roles of presynaptic glutamate receptors continues to grow. Pinheiro and Mulle capture the current state of this knowledge, describing the modes and mechanisms of action of these receptors and the evidence for their contributions to synaptic transmission.

    • Paulo S. Pinheiro
    • Christophe Mulle
    Reviews
    Nature Reviews Neuroscience
    Volume: 9, P: 423-436