Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–3 of 3 results
Advanced filters: Author: "Christopher M Dobson" Clear advanced filters

  • Proteins can self-assemble into functional states, or they can end up as aberrant and sometimes toxic aggregates. Metastable intermediate states are often detected in these processes, and their structural characterization provides vital information about the balance between functional and pathological behavior in living systems.

    • Michele Vendruscolo
    • Christopher M Dobson
    News & Views
    Nature Chemical Biology
    Volume: 9, P: 216-217

  • Protein aggregation causes problems for biotechnology and leads to many fatal human diseases. But a grasp of the physical principles involved enables 'superproteins' to be designed that have exceptional solubilities.

    • Michele Vendruscolo
    • Christopher M. Dobson
    News & Views
    Nature
    Volume: 449, P: 555

  • Protein aggregation and amyloid deposition are associated with a wide range of medical disorders, including Alzheimer's disease and type II diabetes. Studies into the amyloid state are revealing fundamental principles that underlie the maintenance of protein homeostasis, and the origins of aberrant protein behaviour and disease.

    • Tuomas P. J. Knowles
    • Michele Vendruscolo
    • Christopher M. Dobson
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 15, P: 384-396