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Advanced filters: Author: "Christopher N Hahn" Clear advanced filters

  • Recent studies, including two in this issue, report heterozygous missense mutations in the U2AF1 and SF3B1 genes that encode spliceosome subunits. U2AF1 is frequently mutated in myeloid hematopoietic malignancies, especially in myelodysplastic syndrome (MDS), and SF3B1 is frequently mutated in both MDS and chronic lymphocytic leukemia (CLL).

    • Christopher N Hahn
    • Hamish S Scott
    News & Views
    Nature Genetics
    Volume: 44, P: 9-10