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Showing 1–6 of 6 results
Advanced filters: Author: "Craig B Thompson" Clear advanced filters
  • Signalling is known to regulate metabolism, and it is becoming clear that this regulation is reciprocal, with signalling pathways being regulated by the availability of nutrient-sensitive modifications, such as acetylation and glycosylation. This tight link between signalling and metabolism allows cells to modulate their activities according to metabolic status.

    • Kathryn E. Wellen
    • Craig B. Thompson
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 13, P: 270-276
  • Interest in the abnormal metabolism exhibited by cancer cells has been reawakened by the discovery of oncogenic mutations in metabolic enzymes, and by tools that monitor metabolism in living cells. Existing and emerging therapies aim to target this abnormal metabolism in various ways.

    • William G. Kaelin Jr
    • Craig B. Thompson
    Comments & Opinion
    Nature
    Volume: 465, P: 562-564
  • STIM proteins sense subtle changes in the levels of endoplasmice reticulum (ER)-stored Ca2+ and respond by regulating extracellular Ca2+entry and cell signalling. New structural and functional data have shed light on the role of STIM proteins as stress sensors.

    • Jonathan Soboloff
    • Brad S. Rothberg
    • Donald L. Gill
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 13, P: 549-565