Patients with multiple sclerosis (MS) frequently experience depression, which profoundly reduces quality of life, and increases disease mortality. In this Review, Feinstein and colleagues present multiple approaches to the diagnosis and quanitfication of mood disorders, and critically evaluate the various treatment options for MS-related depression.The authors also discuss the extent to which depression can be teased apart from the neurological, immunological and psychosocial sequelae of MS.
- Anthony Feinstein
- Sandra Magalhaes
- Craig Moore
