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Showing 1–4 of 4 results
Advanced filters: Author: "D Fitzgerald" Clear advanced filters

  • In this Review, Liston et al. discuss the biology of regulatory T cells (Treg cells) in the brain. They consider how Treg cells are recruited to the brain and their anti-inflammatory and reparative functions in brain tissue. Finally, they highlight the potential for targeting brain Treg cells to treat a range of neurological diseases.

    • Adrian Liston
    • Emanuela Pasciuto
    • Lidia Yshii
    Reviews
    Nature Reviews Immunology
    Volume: 24, P: 326-337

  • Regeneration of myelin is a dynamic, yet enigmatic process. Dombrowski et al. uncover a central role for regulatory T (Treg) cells in driving oligodendrocyte differentiation, in part via CCN3, a novel factor in Treg function and oligodendrocyte biology. This identifies Treg cells as key cellular players in efficient remyelination.

    • Yvonne Dombrowski
    • Thomas O'Hagan
    • Denise C Fitzgerald
    Research
    Nature Neuroscience
    Volume: 20, P: 674-680