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Showing 1–4 of 4 results
Advanced filters: Author: "D. Branch Moody" Clear advanced filters

  • T cells of the immune system recognize lipids, as well as peptides, extending our ideas about such target antigens. A crystal structure of a T-cell receptor docked to antigen shows how a sugar controls lipid recognition.

    • D. Branch Moody
    News & Views
    Nature
    Volume: 448, P: 36-37

  • This Review focuses on the lesser studied antigen-presenting molecules group 1 CD1 proteins and MHC class I-related protein (MR1). The authors explain how their mode of presentation of lipids and small molecules to T cells differs from that of peptide–MHC presentation, and how new technologies are revealing unique T cell subsets that are specific for CD1 and MR1 proteins.

    • Ildiko Van Rhijn
    • Dale I. Godfrey
    • D. Branch Moody
    Reviews
    Nature Reviews Immunology
    Volume: 15, P: 643-654