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Showing 1–5 of 5 results
Advanced filters: Author: "Dai Fukumura" Clear advanced filters

  • Technological advances in optical coherence tomography (OCT) have enabled this imaging tool to be used to characterize various aspects of tumour biology in vivo. This Innovation article discusses the distinguishing features of OCT, its successful preclinical applications and its potential for clinical adoption.

    • Benjamin J. Vakoc
    • Dai Fukumura
    • Brett E. Bouma
    Reviews
    Nature Reviews Cancer
    Volume: 12, P: 363-368

  • Nitric oxide (NO) and nitric oxide synthases are ubiquitous in malignant tumours, and have both pro- and anti-tumour effects. This review summarizes the current understanding of the function of NO in tumour progression and discusses potential NO-based strategies for cancer treatment.

    • Dai Fukumura
    • Satoshi Kashiwagi
    • Rakesh K. Jain
    Reviews
    Nature Reviews Cancer
    Volume: 6, P: 521-534

  • Brain metastases remain a serious obstacle in the successful treatment of patients with solid tumors. This Review discusses what is known about the biology of brain metastases, what preclinical models are available to study the disease, and which novel therapeutic strategies are being studied in patients.

    • April F. Eichler
    • Euiheon Chung
    • Rakesh K. Jain
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 8, P: 344-356