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Showing 1–3 of 3 results
Advanced filters: Author: "Dan R. Littman" Clear advanced filters

  • The transcription factors Tcf1 and Lef1 have intrinsic histone-deacetylase activity that is required for the repression of CD4+ T cell–lineage genes in CD8+ T cells.

    • Charles P Ng
    • Dan R Littman
    News & Views
    Nature Immunology
    Volume: 17, P: 615-616

  • What factors determine the development of γδ versus αβ T lineage cells from common thymocyte progenitor cells? Here, the authors discuss the two prevailing models for γδ versus αβ T cell development and discuss recent evidence that supports a T cell receptor signal strength model for γδ T cell lineage specification.

    • Maria Ciofani
    • Juan Carlos Zúñiga-Pflücker
    Reviews
    Nature Reviews Immunology
    Volume: 10, P: 657-663