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Showing 1–2 of 2 results
Advanced filters: Author: "Daniel H D Gray" Clear advanced filters

  • The colonization of the colon with commensal microflora drives the induction and population expansion of regulatory T cells, an immunological adaption needed to prevent mucosal inflammation. The epigenetic modifier Uhrf1 acts as a key molecular mediator of such expansion and the establishment of a harmonious mucosal environment.

    • Daniel H D Gray
    • Adrian Liston
    News & Views
    Nature Immunology
    Volume: 15, P: 533-534

  • Regulatory T (TReg) cells are crucial for maintaining immune homeostasis in the body, with recent data showing that distinct TReg cell subsets become specialized to function in different tissues. Here, Liston and Gray highlight the need to regulate the number and function of the TReg cells themselves, and they describe the dynamic processes that achieve this homeostasis and functional specialization of TRegcell subsets.

    • Adrian Liston
    • Daniel H. D. Gray
    Reviews
    Nature Reviews Immunology
    Volume: 14, P: 154-165