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Showing 1–3 of 3 results
Advanced filters: Author: "Daniel J Campbell" Clear advanced filters
  • How B cell tolerance is retained during somatic hypermutation in germinal centers is incompletely understood. Two studies now show that Foxp3+ regulatory T cells undergo functional specialization to limit the magnitude of the germinal center response, and they may contribute to our understanding of how germinal center–mediated autoimmunity is prevented (pages 975–982 and 983–988).

    • Daniel J Campbell
    • Meghan A Koch
    News & Views
    Nature Medicine
    Volume: 17, P: 929-930
  • The transcription factor forkhead box P3 (FOXP3) is essential for the development and function of regulatory T cells. Here, the authors propose that FOXP3 might also influence how a cell responds to T-cell receptor stimulation and what tissue-homing receptors it expresses.

    • Daniel J. Campbell
    • Steven F. Ziegler
    Reviews
    Nature Reviews Immunology
    Volume: 7, P: 305-310
  • This Review describes the recent progress we have made in understanding how regulatory T cell responses are tailored according to the particular nature of the immune environment. The authors discuss the implications for developing new therapies that harness the functions of regulatory T cells.

    • Daniel J. Campbell
    • Meghan A. Koch
    Reviews
    Nature Reviews Immunology
    Volume: 11, P: 119-130