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Advanced filters: Author: "David B. Lombard" Clear advanced filters

  • Increased expression of sirtuin proteins has been shown to enhance lifespan in several organisms. New data indicate that some of the reported effects may have been due to confounding factors in experimental design. Here, experts discuss the significance of these data for research into ageing. See Letter p.482

    • David B. Lombard
    • Scott D. Pletcher
    • Johan Auwerx
    News & Views
    Nature
    Volume: 477, P: 410-411

  • Debates over the role of sirtuin proteins in ageing are maturing into functional assessments of the individual proteins. It seems that overexpression of a specific sirtuin can extend lifespan in male mice. See Letter p.218

    • David B. Lombard
    • Richard A. Miller
    News & Views
    Nature
    Volume: 483, P: 166-167