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Showing 1–3 of 3 results
Advanced filters: Author: "David E. Fisher" Clear advanced filters

  • There are multiple subclasses of melanoma that are partly categorized on the basis of their oncogenic molecular drivers. As discussed in this Review, the understanding of the molecular features of melanoma has led to several exciting advances in the treatment of patients with melanoma.

    • Keith T. Flaherty
    • F. Stephen Hodi
    • David E. Fisher
    Reviews
    Nature Reviews Cancer
    Volume: 12, P: 349-361

  • Genome-based cancer therapeutic matching is limited by incomplete biological understanding of the relationship between phenotype and cancer genotype. This Opinion article proposes that this limitation can be addressed by functional testing of live patient tumour cells exposed to potential therapies.

    • Adam A. Friedman
    • Anthony Letai
    • Keith T. Flaherty
    Reviews
    Nature Reviews Cancer
    Volume: 15, P: 747-756