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Advanced filters: Author: "David E. Gloriam" Clear advanced filters

  • A system has been devised that computationally screens hundreds of millions of drug candidates — all of which can be made on demand — against biological targets. This could help to make drug discovery more efficient.

    • David E. Gloriam
    News & Views
    Nature
    Volume: 566, P: 193-194

  • G protein-coupled receptors (GPCRs) are the most intensively studied class of drug targets. This article presents a pioneering analysis of all GPCR-targeted drugs and agents that are currently in clinical trials, and discusses the trends across molecule types, drug targets and therapeutic indications.

    • Alexander S. Hauser
    • Misty M. Attwood
    • David E. Gloriam
    Research
    Nature Reviews Drug Discovery
    Volume: 16, P: 829-842