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Showing 1–4 of 4 results
Advanced filters: Author: "David J Mooney" Clear advanced filters

  • The spreading and differentiation of stem cells depends on the stiffness of the extracellular matrix. Now, experiments on human epidermal and mesenchymal stem cells cultured on substrates with covalently attached collagen fibres show that the cells sense and respond to the anchoring of the collagen fibres to the substrate.

    • Ovijit Chaudhuri
    • David J. Mooney
    News & Views
    Nature Materials
    Volume: 11, P: 568-569

  • Wall paint gives the best result if the surface is primed with an undercoat. The same concept, applied to biomaterials, yields successful fixation of implant and tissue integration.

    • David J. Mooney
    • Eduardo A. Silva
    News & Views
    Nature Materials
    Volume: 6, P: 327-328

  • Physical cues regulate stem cell fate and function during embryonic development and in adult tissues. The biophysical and biochemical properties of the stem cell microenvironment can be precisely manipulated using synthetic niches, which provide key insights into how mechanical stimuli regulate stem cell function and can be used to maintain and guide stem cells for regenerative therapies.

    • Kyle H. Vining
    • David J. Mooney
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 18, P: 728-742