Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–3 of 3 results
Advanced filters: Author: "David J. A. Wyllie" Clear advanced filters

  • A single amino acid residue determines single-channel conductance, ion permeation and channel block in the NMDA receptor, three of the key features of this ligand-gated ion channel.

    • David J A Wyllie
    • Stephen F Traynelis
    News & Views
    Nature Neuroscience
    Volume: 15, P: 343-344

  • Fragile X syndrome and autism spectrum disorders are associated with circuit hyperexcitability, however, its cellular and synaptic bases are not well understood. Here, the authors report abnormal synaptogenesis with an increased prevalence of polysynaptic spines with normal morphology in a mouse model of fragile X.

    • Sam A. Booker
    • Aleksander P. F. Domanski
    • Peter C. Kind
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14

  • Repeat expansion mutation in C9ORF72 is the most common cause of familial ALS. Here, the authors generate motor neurons from cells of patients with C9ORF72 mutations, and characterize changes in gene expression in these motor neurons compared to genetically corrected lines, which suggest that glutamate receptor subunit GluA1 is dysregulated in this form of ALS.

    • Bhuvaneish T. Selvaraj
    • Matthew R. Livesey
    • Siddharthan Chandran
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14