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Showing 1–3 of 3 results
Advanced filters: Author: "David Reich" Clear advanced filters

  • This article compares the different approaches that have been developed for detecting confounding due to population stratification, family structure and cryptic relatedness, with an emphasis on the potential of mixed models for addressing these problems simultaneously.

    • Alkes L. Price
    • Noah A. Zaitlen
    • Nick Patterson
    Reviews
    Nature Reviews Genetics
    Volume: 11, P: 459-463

    • Alkes L. Price
    • Noah A. Zaitlen
    • Nick Patterson
    Correspondence
    Nature Reviews Genetics
    Volume: 14, P: 300

  • Principal component analysis (PCA) has been a useful tool for analysis of genetic data, particularly in studies of human migration. A new study finds evidence that the observed geographic gradients, traditionally thought to represent major historical migrations, may in fact have other interpretations.

    • David Reich
    • Alkes L Price
    • Nick Patterson
    News & Views
    Nature Genetics
    Volume: 40, P: 491-492