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Showing 1–2 of 2 results
Advanced filters: Author: "Davide Corti" Clear advanced filters

  • Therapeutics to combat multidrug-resistant bacteria such as Klebsiella pneumoniae are needed. Here the authors show immune evasion drives lipopolysaccharide O2 serotype expansion in multidrug-resistant isolates, and anti-O-antigen human monoclonal antibodies synergize with antibiotics to protect mice from infection.

    • Meghan E. Pennini
    • Anna De Marco
    • C. Kendall Stover
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12

  • A human monoclonal antibody has been identified which can cross-neutralize both human respiratory syncytial virus (HRSV) and human metapneumovirus (HMPV), demonstrating that a single monoclonal antibody can target different viruses, a discovery that may lead to the creation of new therapeutics and vaccines.

    • Davide Corti
    • Siro Bianchi
    • Antonio Lanzavecchia
    Research
    Nature
    Volume: 501, P: 439-443