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Showing 1–2 of 2 results
Advanced filters: Author: "Dean A. Fennell" Clear advanced filters

  • Major advances in the first-line therapy of inoperable malignant pleural mesothelioma have occurred in the past 5 years. This Review summarizes evidence supporting the clinical activity of chemotherapy, discusses the use of end points for its assessment, and the influence of clinical and biochemical prognostic factors on the natural history of malignant pleural mesothelioma.

    • Dean A Fennell
    • Giovanni Gaudino
    • Jan van Meerbeeck
    Reviews
    Nature Clinical Practice Oncology
    Volume: 5, P: 136-147

  • Our understanding of mesothelioma pathobiology has increased dramatically in the past 5 years, with an improvement in our knowledge of mesothelioma genetics, epigenetics, tumour microenvironment and immunobiology. This Review discusses these advances and how they might affect therapeutic strategies.

    • Timothy A. Yap
    • Joachim G. Aerts
    • Dean A. Fennell
    Reviews
    Nature Reviews Cancer
    Volume: 17, P: 475-488