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Showing 1–3 of 3 results
Advanced filters: Author: "Dean Felsher" Clear advanced filters

  • Recently, MYC has been shown to serve as a direct regulator of ribosome biogenesis and therefore coordinates protein synthesis. Could the regulation of ribosome biogenesis by MYC be necessary for its role in tumorigenesis?

    • Jan van Riggelen
    • Alper Yetil
    • Dean W. Felsher
    Reviews
    Nature Reviews Cancer
    Volume: 10, P: 301-309

  • The passage of transcription factors in and out of the nucleus must be regulated for their proper function. Surprisingly, regulation of nuclear trafficking among members of the signal transducer and activator of transcription (STAT) family differs, revealing specific targets for therapeutic intervention.

    • Nancy C. Reich
    • Ling Liu
    Reviews
    Nature Reviews Immunology
    Volume: 6, P: 602-612