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Showing 1–2 of 2 results
Advanced filters: Author: "Derek P. Narendra" Clear advanced filters

  • Mitophagy is the selective elimination of mitochondria through autophagy. Recent studies have uncovered the molecular mechanisms mediating mitophagy in yeast and mammalian cells and have revealed that the dysregulation of one of these mechanisms — the PINK1–parkin-mediated signalling pathway — may contribute to Parkinson's disease.

    • Richard J. Youle
    • Derek P. Narendra
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 12, P: 9-14

  • Studies of rare hereditary disorders are intended to find treatments, but they can also bring other discoveries. One such study links the dysfunction of a protein to that of the cell's energy producers, the mitochondria.

    • Derek P. Narendra
    • Richard J. Youle
    News & Views
    Nature
    Volume: 483, P: 418-419