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Showing 1–3 of 3 results
Advanced filters: Author: "Donald E Ingber" Clear advanced filters

  • Mechanical forces that are exerted on surface-adhesion receptors can be channelled along cytoskeletal filaments and concentrated at distant sites in the cytoplasm and nucleus. How do these forces act at a distance to induce mechanochemical conversion in the nucleus, and what effects can they have on the cell?

    • Ning Wang
    • Jessica D. Tytell
    • Donald E. Ingber
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 10, P: 75-82

  • A recent advance has led to the development of microfluidically linked microphysiological culture systems that mimic the complex dynamics and interdependent physiology of the various organs that comprise the female reproductive tract. This microfluidic culture platform offers an unprecedented way to study female reproductive biology and develop new reproductive therapeutics.

    • Donald E. Ingber
    News & Views
    Nature Reviews Endocrinology
    Volume: 13, P: 380-382

  • In this Opinion article, Brocket al. analyse how intrinsic variability in gene expression in proliferating cells, as well as microenvironmental signals, can drive cells to transform into a neoplastic state or revert to a normalized state.

    • Amy Brock
    • Silva Krause
    • Donald E. Ingber
    Reviews
    Nature Reviews Cancer
    Volume: 15, P: 499-509