Current rehabilitative strategies for children with unilateral cerebral palsy (UCP) focus on activity-based tasks, but a greater understanding of the condition and the way in which the brain responds to therapy could enable the development of more-effective approaches. In this Review, the authors first discuss current rehabilitative strategies and the factors that are crucial to their success. They then consider in detail how neuroimaging is informing us about the neurobiology of UCP and the neuroplasticity in the brains of children with the condition, and how this knowledge could transform therapy.
- Lee B. Reid
- Stephen E. Rose
- Roslyn N. Boyd
